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Yıl:2012; Cilt: 22; Sayı: 2>> Özet
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Klinik Psikofarmakoloji Bülteni; 2012;22(2):184-186
Olanzapine bağlı hipernatremi ile giden malign nöroleptik sendrom
R Tutuncu, H Gunay, H Balibey
Etimesgut Military Hospital, Ankara - Turkey
Malign Nöroleptik Sendrom (MNS) antipsikotiklerin nadir görülen fakat ölümcül olabilen bir yan etkisidir. MNS’nin ortaya çıkışında hipernatreminin önemli rolü olabilir ya da akut böbrek yetmezliğine ikincil olarak gelişebilir. Bu yazıda, olanzapin ile tedavi sonrası MNS, hipernatremi ve akut böbrek yetmezliği gelişen 27 yaşında bir erkek hasta bildirilmektedir.
Olanzapine-induced neuroleptic malignant syndrome with hypernatremia
Neuroleptic Malignant syndrome (NMS) is a rare but potentially fatal adverse effect of antipsychotics. In addition, hypernatremia may play a significant role before occurrence of NMS or it may develop secondary to acute renal failure. Herein we report the case of a 27 [year] old male patient who developed NMS with hypernatremia and acute renal failure following treatment with olanzapine.

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