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Yıl:2023; Cilt: 60; Sayı: 1>> Özet
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Nöropsikiyatri Arşivi; 2023;60(1):81-86
Türkiye’deki COVID-19 Hastalarının Baş Ağrısı Özellikleri: COVID-19 Enfeksiyonu Migren için Bir Tetikleyici midir?
Y Hacıoğlu, R G Gözübatık-Çelik, O Yenidünya, Ö Kesmezacar, U E Toprak
İstanbul Eğitim ve Araştırma Hastanesi, İstanbul
Amaç: Baş ağrısı, koronavirüs-19 enfeksiyonu (COVID-19) olan hastalarda sık görülen bir semptomdur. Bu araştırmada, Türkiye’de COVID-19 hastalarında baş ağrısının sıklığını, özelliklerini, tedaviye yanıtını ve psikososyal özelliklerle ilişkisini değerlendirmeyi amaçladık. Yöntem: Pandemi sırasında COVID-19 pozitif bireylerde baş ağrısının klinik özelliklerini tanımlamak için üçüncü basamak özelliğindeki eğitim ve araştırma hastanesinde hastalar yüz yüze vizitlerle değerlendirildi ve takip edildi. Bulgular: 150 hastanın 117’sinde (%78) pandemi öncesi ve pandemi sırasında baş ağrısı vardı. 150 hastanın 62’si (%41,3) yeni bir baş ağrısına sahipti. Baş ağrısı olan ve olmayan hastalar arasında demografik özellikler, Beck Depresyon Skoru, Beck Anksiyete Skoru ve yaşam kalitesi ölçekleri (QOLS) açısından anlamlı fark bulunmadı (p>0.05). Baş ağrısı için en yaygın tetikleyici faktör %59 (n=69) ile stres ve yorgunluk iken, ikinci en yaygın (%32,4, n=38) COVID-19 enfeksiyonuydu. Hastaların %46,5’i COVID-19 enfeksiyonundan sonra mevcut baş ağrılarının şiddetinin ve sıklığının arttığını bildirdi. Yeni başlayan baş ağrılarında yaşam kalitesi formunun sosyal işlevsellik ve ağrı skoru alt grupları ev hanımlarında ve işsiz hastalarda çalışan gruba göre anlamlı olarak daha düşüktü (sırasıyla p=0,018; p=0,039). Yüz on yedi hastanın 12’sinde, temporoparietal bölgede, Uluslararası Baş Ağrısı Bozuklukları Sınıflandırması kriterlerini karşılamayan, ancak COVID-19 hastaları arasında ortak bir özellik olarak görülen hafif ile orta şiddette, zonklayıcı bir baş ağrısı vardı. Altmış iki hastanın 19’u (%30.9) yeni migren tanısı aldı. Sonuç: COVID-19 hastalığı olan hastalarda migren insidansının diğer baş ağrısı türlerine göre daha fazla artması olası immun mekanizmalarla ortak bir yolun varlığını düşündürmektedir.
Headache Characteristics of Patients with COVID-19 in Turkey: Is COVID-19 Infection a Trigger for Migraine Headache?
Introduction: Headache is a common symptom in patients with Coronavirus-19 infection (COVID-19). In this research, we aim to assess the frequency, characteristics, and response to treatment of headache in patients with COVID-19 and its correlation with psychosocial features in Turkey. Methods: To describe the clinical features of headache in COVID-19 positive individuals. Patients were evaluated and followed up with faceto-face visits in a tertiary hospital during the pandemic period. Results: One hundred and seventeen of 150 patients (78%) had a headache diagnosed before and during the pandemic, 62 of 150 (41.3%) had a new type of headache. No significant differences were observed in terms of demographics, Beck Depression Score, Beck Anxiety Score, and quality of life scales (QOLS) between patients with and without headache (p>0.05). The most common triggering factor for headache was stress and fatigue in 59% (n=69), while the second most common (32.4%, n=38) was COVID-19 infection. 46.5% of the patients reported that the severity and frequency of their current headaches increased after the COVID-19 infection. Among new-onset headaches, the social functionality and pain score subgroups of the QOLS form were significantly lower in housewives and unemployed patients compared to the working group (p=0.018; p=0.039 respectively). Twelve of 117 patients had a mild to moderate, throbbing headache in the temporoparietal region, which did not fulfill the International Classification of Headache Disorders diagnosis criteria, but showed as a common feature among COVID-19 patients. Nineteen of 62 patients (30.9%) had a newly diagnosed migraine syndrome. Conclusion: The diagnosis incidence of migraine in patients with COVID-19 disease being more than other headaches types may suggest the existence of a common pathway in possible immune mechanisms.

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