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Yıl:2010; Cilt: 20; Sayı: 3>> Özet
TAM METİN
Klinik Psikofarmakoloji Bülteni; 2010;20(3):252-254
Olanzapin kullanımına bağlı tardif distoni olgusu
E Göka, E Ak, SD Bulut, Ç Aydemir, C Kısa
Ankara Numune Hastanesi
Tardif distoni (TD) antipsikotik ajanlar tarafından indüklenen, ekstremiteleri, gövdeyi ve yüz bölgesini etkileyen, bölgesel veya genel, devamlı, genellikle yavaş, istemsiz kıvrılma/bükülme hareketlerdir. Bir atipik antipsikotik olan olanzapinin klasik antipsikotiklere göre ekstrapiramidal yan etkilerinin daha az olduğu bilinmektedir. Bununla birlikte birçok vakada TD tedavisinde etkili olan olanzapinin bazı vakalarda da TD'ye neden olduğu bildirilmiştir. Bu yazıda 2 yıl olanzapin kullanan ve şizofreni tanısı olan bir hastada ortaya çıkan tardiv distoni olgusu ve sonrasındaki tedavi yaklaşımı sunuldu.
Olanzapine induced tardive dystonia: a case report
Tardive dystonia (TD) is a movement disorder induced by antipsychotic agents, seen in extremities, face, and trunk. TD movements can be regional or generalized and are continuous and slow involuntary swirl or convolution movements. It is known that olanzapine as an atypical antipsychotic drug causes less extrapyramidal side effects than typical ones do. Furthermore it's recommended as treatment for TD cases caused by other antipsychotic treatments. On the other hand few olanzapine induced TD cases were reported in the literature. In this report, a tardive dystonia case developed in a schizophrenic patient, who was treated with olanzapine for two [year]s and treatment approach after TD, was presented.

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